NlmeResidualEffect-class

NlmeResidualEffect

Class represents an NLME/PML residual error model

internal

Facilitate Pharmacokinetic (PK) and Pharmacodynamic (PD) modeling
and simulation with powerful tools for Nonlinear Mixed-Effects (NLME)
modeling. The package provides access to the same advanced Maximum Likelihood
algorithms used by the NLME-Engine in the Phoenix platform. These tools support
a range of analyses, from parametric methods to individual and pooled data, and
support integrated use within the Pirana pharmacometric workbench
<doi:10.1002/psp4.70067>. Execution is supported both locally or on
remote machines.

James Craig

Certara.RsNLME

Pharmacometric Modeling

Michael Tomashevskiy

Vitalii Nazarov

Shuhua Hu

Soltanshahi Fred

Certara USA, Inc. 

NlmeResidualEffect-class function

<dl><dt>effectName</dt>
<dd>Name of the observed variable</dd>
<dt>observeName</dt>
<dd>Name to use for observation</dd>
<dt>epsilonName</dt>
<dd>Name to use for Epsilon</dd>
<dt>errorType</dt>
<dd>Additive|LogAdditive|Multiplicative
|AdditiveMultiplicative|MixRatio|Power|Custom</dd>
<dt>frozen</dt>
<dd>Is the standard deviation frozen? (Default:FALSE)</dd>
<dt>SD</dt>
<dd>Standard deviation value</dd>
<dt>definition</dt>
<dd>Definition of a custom type or Power value</dd>
<dt>isBQL</dt>
<dd>Are there BQL values? (Default:FALSE)</dd>
<dt>bqlStatic</dt>
<dd>Value LLOQ value</dd>
<dt>dobefore</dt>
<dd>Code to execute before the observation</dd>
<dt>doafter</dt>
<dd>Code to execute after the observation</dd></dl>

Arguments

Class represents an NLME/PML residual error model — NlmeResidualEffect-class

<dl>

<dt>effectName</dt>
<dd>Name of the observed variable</dd>


<dt>observeName</dt>
<dd>Name to use for observation</dd>


<dt>epsilonName</dt>
<dd>Name to use for Epsilon</dd>


<dt>errorType</dt>
<dd>Additive|LogAdditive|Multiplicative
|AdditiveMultiplicative|MixRatio|Power|Custom</dd>


<dt>frozen</dt>
<dd>Is the standard deviation frozen? (Default:FALSE)</dd>


<dt>SD</dt>
<dd>Standard deviation value</dd>


<dt>definition</dt>
<dd>Definition of a custom type or Power value</dd>


<dt>isBQL</dt>
<dd>Are there BQL values? (Default:FALSE)</dd>


<dt>bqlStatic</dt>
<dd>Value LLOQ value</dd>


<dt>dobefore</dt>
<dd>Code to execute before the observation</dd>


<dt>doafter</dt>
<dd>Code to execute after the observation</dd>

</dl>

NlmeResidualEffect-class: Class represents an NLME/PML residual error model

Description

Arguments