StepwiseParams-class

StepwiseParams

Class represents an NLME Stepwise search parameters

internal

Facilitate Pharmacokinetic (PK) and Pharmacodynamic (PD) modeling
and simulation with powerful tools for Nonlinear Mixed-Effects (NLME)
modeling. The package provides access to the same advanced Maximum Likelihood
algorithms used by the NLME-Engine in the Phoenix platform. These tools support
a range of analyses, from parametric methods to individual and pooled data, and
support integrated use within the Pirana pharmacometric workbench
<doi:10.1002/psp4.70067>. Execution is supported both locally or on
remote machines.

James Craig

Certara.RsNLME

Pharmacometric Modeling

Michael Tomashevskiy

Vitalii Nazarov

Shuhua Hu

Soltanshahi Fred

Certara USA, Inc. 

StepwiseParams-class function

<dl><dt>addPValue</dt>
<dd>Numeric. Threshold for adding a covariate effect</dd>
<dt>removePValue</dt>
<dd>Numeric. Threshold for removing a covariate effect</dd>
<dt>method</dt>
<dd>-2LL|AIC|BIC; could be abbreviated.</dd></dl>

Arguments

Class initializer for NLME StepwiseParams — StepwiseParams-class

<dl>

<dt>addPValue</dt>
<dd>Numeric. Threshold for adding a covariate effect</dd>


<dt>removePValue</dt>
<dd>Numeric. Threshold for removing a covariate effect</dd>


<dt>method</dt>
<dd>-2LL|AIC|BIC; could be abbreviated.</dd>

</dl>

StepwiseParams-class: Class initializer for NLME StepwiseParams

Description

Arguments

Examples