pkData

Pharmacokinetic dataset containing 16 subjects with single bolus dose.

datasets

Facilitate Pharmacokinetic (PK) and Pharmacodynamic (PD) modeling
and simulation with powerful tools for Nonlinear Mixed-Effects (NLME)
modeling. The package provides access to the same advanced Maximum Likelihood
algorithms used by the NLME-Engine in the Phoenix platform. These tools support
a range of analyses, from parametric methods to individual and pooled data, and
support integrated use within the Pirana pharmacometric workbench
<doi:10.1002/psp4.70067>. Execution is supported both locally or on
remote machines.

James Craig

Certara.RsNLME

Pharmacometric Modeling

Michael Tomashevskiy

Vitalii Nazarov

Shuhua Hu

Soltanshahi Fred

Certara USA, Inc. 

pkData function

A data frame with 112 rows and 8 variables:<dl>
 <dt>Subject</dt>
<dd>Subject ID</dd> <dt>Nom_Time</dt>
<dd>Nominal Time</dd> <dt>Act_Time</dt>
<dd>Actual Time</dd> <dt>Amount</dt>
<dd>Amount of dose</dd> <dt>Conc</dt>
<dd>Observations of drug concentration in blood</dd> <dt>Age</dt>
<dd>Age</dd> <dt>BodyWeight</dt>
<dd>Body weight</dd> <dt>Gender</dt>
<dd>Gender ("male", "female")</dd>
</dl>

Format

Pharmacokinetic dataset containing 16 subjects with single bolus dose — pkData

A data frame with 112 rows and 8 variables:<dl>
 <dt>Subject</dt>
<dd>Subject ID</dd>

 <dt>Nom_Time</dt>
<dd>Nominal Time</dd>

 <dt>Act_Time</dt>
<dd>Actual Time</dd>

 <dt>Amount</dt>
<dd>Amount of dose</dd>

 <dt>Conc</dt>
<dd>Observations of drug concentration in blood</dd>

 <dt>Age</dt>
<dd>Age</dd>

 <dt>BodyWeight</dt>
<dd>Body weight</dd>

 <dt>Gender</dt>
<dd>Gender ("male", "female")</dd>


</dl>

pkData: Pharmacokinetic dataset containing 16 subjects with single bolus dose

Description

Usage

Arguments

Format