pkpdData

Pharmacokinetic/Pharmacodynamic dataset containing 200 subjects with single bolus dose.

datasets

Facilitate Pharmacokinetic (PK) and Pharmacodynamic (PD) modeling
and simulation with powerful tools for Nonlinear Mixed-Effects (NLME)
modeling. The package provides access to the same advanced Maximum Likelihood
algorithms used by the NLME-Engine in the Phoenix platform. These tools support
a range of analyses, from parametric methods to individual and pooled data, and
support integrated use within the Pirana pharmacometric workbench
<doi:10.1002/psp4.70067>. Execution is supported both locally or on
remote machines.

James Craig

Certara.RsNLME

Pharmacometric Modeling

Michael Tomashevskiy

Vitalii Nazarov

Shuhua Hu

Soltanshahi Fred

Certara USA, Inc. 

pkpdData function

A data frame with 2600 rows and 5 variables:<dl>
 <dt>ID</dt>
<dd>Subject ID</dd> <dt>Time</dt>
<dd>Nominal Time</dd> <dt>Dose</dt>
<dd>Amount of dose</dd> <dt>CObs</dt>
<dd>Observations of drug concentration in blood</dd> <dt>EObs</dt>
<dd>Observations of drug effect</dd>
</dl>

Format

Pharmacokinetic/Pharmacodynamic dataset containing 200 subjects with single bolus dose — pkpdData

A data frame with 2600 rows and 5 variables:<dl>
 <dt>ID</dt>
<dd>Subject ID</dd>

 <dt>Time</dt>
<dd>Nominal Time</dd>

 <dt>Dose</dt>
<dd>Amount of dose</dd>

 <dt>CObs</dt>
<dd>Observations of drug concentration in blood</dd>

 <dt>EObs</dt>
<dd>Observations of drug effect</dd>


</dl>

pkpdData: Pharmacokinetic/Pharmacodynamic dataset containing 200 subjects with single bolus dose

Description

Usage

Arguments

Format