ClassifyR (version 1.2.4)

DMDselection: Selection of Differential Distributions with Kullback Leibler Distance

Description

Ranks features by largest Differences in Means/Medians and Deviations and chooses the features which have best resubstitution performance.

Usage

"DMDselection"(expression, classes, ...) "DMDselection"(expression, trainParams, predictParams, resubstituteParams, ..., verbose = 3)

Arguments

expression

Either a matrix or ExpressionSet containing the training data. For a matrix, the rows are features, and the columns are samples.

classes

A vector of class labels.

trainParams

A container of class TrainParams describing the classifier to use for training.

predictParams

A container of class PredictParams describing how prediction is to be done.

resubstituteParams

An object of class ResubstituteParams describing the performance measure to consider and the numbers of top features to try for resubstitution classification.

...

Variables passed to getLocationsAndScales.

verbose

A number between 0 and 3 for the amount of progress messages to give. This function only prints progress messages if the value is 3.

Value

A list of length 2. The first element has the features ranked from most important to least important. The second element has the features that were selected to be used for classification.

Details

DMD is defined as $|location1 - location2| + |scale1 - scale2|$. The subscripts denote the group which the parameter is calculated for.

Examples

  if(require(sparsediscrim))
  {
    # First 25 samples are mixtures of two normals. Last 25 samples are one normal.
    genesMatrix <- sapply(1:25, function(geneColumn) c(rnorm(50, 5, 1), rnorm(50, 15, 1)))
    genesMatrix <- cbind(genesMatrix, sapply(1:25, function(geneColumn) rnorm(100, 9, 3)))
    classes <- factor(rep(c("Poor", "Good"), each = 25))
    DMDselection(genesMatrix, classes,
                 trainParams = TrainParams(), predictParams = PredictParams(),
                 resubstituteParams = ResubstituteParams(nFeatures = seq(10, 100, 10), performanceType = "balanced", better = "lower"))
  }