Estimates the net benefit and standardized net benefit of a risk score given a risk threshold R. Additionally estimates the standardized net benefit of a "treat-all" (everyone recieves intervention) treatment rule.
nb(y, p, r)Vector of binary outcomes, with 1 indicating event (case) and 0 indicating no event (controls)
Vector of risk score values
Clinically relevant risk threshold
Net benefit of risk score \(p\)
Standardized net benefit of risk score \(p\). Net benefit of \(p\) dived by the prevalence
Standardized net benefit of a decision rule where everyone recieves treatment
Pauker, S. G., & Kassirer, J. P. (1980). The threshold approach to clinical decision making. New England Journal of Medicine, 302(20), 1109-1117.
Mishra, A. (2019). Methods for Risk Markers that Incorporate Clinical Utility (Doctoral dissertation). (Available Upon Request)