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CohortPlat

The goal of CohortPlat is to facilitate the simulation of cohort platform trials for combination treatments with binary endpoints.

Installation

You can install the released version of CohortPlat from CRAN with:

install.packages("CohortPlat")

And the development version from GitHub with:

# install.packages("devtools")
devtools::install_github("el-meyer/CohortPlat")

Usage

Please see the reference manual for more information on the usage of this package, or jump directly to the vignette.

Disclaimer

EU-PEARL (EU Patient-cEntric clinicAl tRial pLatforms) project has received funding from the Innovative Medicines Initiative (IMI) 2 Joint Undertaking (JU) under grant agreement No 853966. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation program and EFPIA and Children’s Tumor Foundation, Global Alliance for TB Drug Development non-profit organization, Springworks Therapeutics Inc. This publication reflects the authors’ views. Neither IMI nor the European Union, EFPIA, or any Associated Partners are responsible for any use that may be made of the information contained herein. The research of Elias Laurin Meyer was funded until 11/2020 by Novartis through the University and not at an individual level.

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Version

Install

install.packages('CohortPlat')

Monthly Downloads

248

Version

1.0.5

License

MIT + file LICENSE

Maintainer

Elias Laurin Meyer

Last Published

February 14th, 2022

Functions in CohortPlat (1.0.5)

trial_ocs

Calculates the operating characteristics of the cohort trial
plot_trial

Plots the cohort trial study overview given stage data.
make_decision_trial

Checks whether decision criteria are met and updates trial results accordingly.
simulate_trial

Simulates the cohort trial.