It has been designed to calculate the required sample size in randomized clinical trials with composite endpoints. It also calculates the expected effect and the probability of observing the composite endpoint, among others. The methodology can be found in Bofill & Gómez (2019) tools:::Rd_expr_doi("10.1002/sim.8092") and Gómez & Lagakos (2013) tools:::Rd_expr_doi("10.1002/sim.5547").
Maintainer: Marta Bofill Roig marta.bofill.roig@upc.edu
Authors:
Jordi Cortes Martinez
Other contributors:
Guadalupe Gomez Melis [contributor]
Useful links: