dehp: Developmental toxicology study of DEHP in mice
Description
This data set is based on a National Toxicology Program study on diethylhexyl phthalate, DEHP.
Pregnant CD-1 mice were randomly assigned to receive 0, 250, 500, 1000, or 1500 ppm of DEHP in their feed
during gestational days 0-17. The uterine contents of the mice were examined for toxicity endpoints prior to
normal delivery. The possible outcomes are 1) malformation, 2) death or resorption, 3) no adverse event.format
A 'CMData' object, that is a data frame with the following variables
ll{
Trt factor giving treatment group
ClusterSize the size of the litter
NResp.1 the number of fetuses with a type 1 outcome (malformation)
NResp.2 the number of fetuses with a type 2 outcome (death or resorption)
NResp.3 the number of fetuses with a type 3 outcome (normal)
Freq the number of litters with the given ClusterSize/NResp.1-NResp.3 combination
}source
National Toxicology Program, NTP Study TER84064.References
Tyl, R. W., Price, C. J., Marr, M. C., and Kimmel, C. A. (1988). Developmental toxicity evaluation of dietary
di(2-ethylhexy)phthalate in Fischer 344 rats and CD-1 mice. Fundamental and Applied Toxicology
10, 395-412.