a function to compute a location for a
sample. By default, the median is used. However,
especially for low counts, the
shorth function from the
genefilter package may give better results.
geoMeans
by default this is not provided and the
geometric means of the counts are calculated within the
function. A vector of geometric means from another count
matrix can be provided for a "frozen" size factor
calculation
Value
The DEXSeqDataSet passed as parameters, with the size
factors filled in.
Details
This function calls the method estimateSizeFactors
for the DESeqDataSet object, and adapts it to the
specific use to the DEXSeqDataSet.