Format
A data frame with 98 observations on the following 12 variables.
Z1- a numeric vector giving the estimated Z1 coefficients
of the logistic regression curve.
Z2- a numeric vector giving the estimated Z2 coefficients
of the logistic regression curve.
Z3- a numeric vector giving the estimated Z3 coefficients
of the logistic regression curve.
T1- a numeric vector giving the estimated time point
where the horizontal line of the curve is defined,
i.e., the curve consists of a horizontal line up to
t=T1ji.
T2- a numeric vector giving the estimated time point where
the logistic component of the curve is defined, i.e.,
the curve consist of a logistic regression curve
starting at t=T2ji.
B0- a numeric vector giving the estimated B0 coefficients
of the logistic regression curve.
B1- a numeric vector giving the estimated B1 coefficients
of the logistic regression curve.
CTX- a numeric vector giving the dose level of
cyclophosphamide.
GM- a numeric vector giving the dose level GM-CSF.
AMOF- a numeric vector giving the dose level of
amifostine.
pat- a numeric vector giving the patient indicators.
study- a numeric vector giving the study indicators.
Source
CALGB 8881:
Lichtman, S. M., Ratain, M. J., Echo, D. A., Rosner, G., Egorin, M. J., Budman, D. R.,
Vogelzang,N. J., Norton, L. and Schilsky, R. L. (1993) Phase I trial and granulocyte-macrophage
colony-stimulating factor plus high-dose cyclophosphamide given every 2 weeks: a Cancer and
Leukemia Group B study. Journal of the National Cancer Institute, 85: 1319-1326. CALGB 9160:
Budman, D., Rosner, G., Lichtman, S., Miller, A., Ratain, M. and Schilsky, R. (1998)
A randomized trial of wr-2721 (amifostine) as a chemoprotective agent in combination with
high-dose cyclophosphamide and molgramostim (GM-CSG). Cancer Therapeutics, 1: 164-167.