DPpackage (version 1.1-6)

deterioration: Time to Cosmetic Deterioration of Breast Cancer Patients

Description

This data set considers information of time to cosmetic deterioration of the breast for women with Stage 1 breast cancer who have undergone a lumpectomy, for two treatments, these being radiation, and radiation coupled with chemotherapy. There is interest in the cosmetic impact of the treatments because both are considered very effective in preventing recurrence of this early stage cancer. The data come from a retrospective study of 46 patients who received radiation only and 48 who received radiation plus chemotherapy. Each woman made a series of visits to a clinician, who determined whether or not retraction had occurred. If it had, the time of retraction was known only to lie between the time of the present and last visits. The data set is presented in Beadle et al. (1984a,b) and also given in Finkelstein and Wolfe (1985).

Usage

data(deterioration)

Format

A data frame with 94 observations on the following 3 variables.

left

a numeric vector giving the left limit of the interval

right

a numeric vector giving the right limit of the interval

trt

a numeric vector giving the treatment (0 = radiation only, 1 = radiation plus chemotherapy)

Source

Beadle, G., Come, S., Henderson, C., Silver, B., and Hellman, S. (1984a). The effect of adjuvant chemotherapy on the cosmetic results after primary radiation treatment for early stage breast cancer. International Journal of Radiation Oncology, Biology and Physics, 10: 2131-2137. Beadle, G., Harris, J., Silver, B., Botnick, L., and Hellman, S. (1984b). Cosmetic results following primary radiation therapy for early breast cancer. Cancer, 54: 2911-2918. Finkelstein, D.M. and Wolfe, R.A. (1985). A semiparametric model for regression analysis of interval-censored failure time data. Biometrics, 41: 933-945.

References

Hanson, T., and Johnson, W. (2004) A Bayesian Semiparametric AFT Model for Interval-Censored Data. Journal of Computational and Graphical Statistics, 13: 341-361.

Examples

data(deterioration)
## maybe str(deterioration) ; plot(deterioration) ...