DPpackage (version 1.1-6)

igg: Immunoglobulin G concentrations

Description

This data set consider information on the serum immunoglbulin G (IgG) concentration from 298 children aged 6 months to 6 years old. The data were reported by Isaacs et al. (1983). These data were further analysed by Royston and Wright (1998) and Kapitula and Bedrick (2005) using the parametric exponential normal family, which includes parameters for skew and kurtosis that can be functions of covariates.

Usage

data(igg)

Format

A data frame with 298 observations on the following 2 variables.

age

a numeric vector giving the age of the children (in years).

igg

a numeric vector giving the the serum IgG concentration.

Source

Isaacs, D., Altman, D. G., Tidmarsh, C. E., Valman, H. B., Webster, A. D. B. (1983). Serum immunoglobulin concentrations in preschool children measured by laser nephelometry: reference ranges for IgG, IgA, IgM. J. Clin. Pathol. 36: 1193 - 1196.

References

Kapitula, L. R., Bedrick, E. J. (2005). Diagnostics for the exponential normal growth curve model. Statist. Med. 24: 95 - 108.

Royston, P., Wright, E. M. (1998). A method for estimation age-specific reference intervals ('normal ranges') based on fractional polynomials and exponential transformation. J. R. Statist. Soc. A 161: 79 - 101.

Examples

data(igg)
## maybe str(igg) ; plot(igg) ...