DVHmetrics (version 0.2)

getIsoEffD: 2Gy fractions biologically equivalent dose (EQD2)

Description

Convert given (fractional) dose into an isoeffective (fractional) dose for a different total dose / fractionation schedule according to the linear-quadratic model.

Usage

getIsoEffD(D1=NULL,  D2=NULL,
           fd1=NULL, fd2=NULL,
           fn1=NULL, fn2=NULL, ab=NULL)

Arguments

D1

numeric vector. Total dose 1.

D2

numeric vector. Total dose 2.

fd1

numeric vector. Fractional dose 1.

fd2

numeric vector. Fractional dose 2.

fn1

numeric vector. Number of fractions 1.

fn2

numeric vector. Number of fractions 2.

ab

numeric vector. alpha/beta ratio for the relevant tissue in the linear-quadatic model.

Value

• The (vector of) isoeffective (fractional) dose value(s)

Details

Either calculate D2 based on D1, fd1, fd2, and ab. Or calculate fd2 based on D1, D2, fd1, and ab. Instead of providing D1 (or D2) directly, fd1 AND fn1 (or fd2 AND fn2) can be given.

References

Barendsen, G. W. (1982) Dose fractionation, dose-rate and iso-effect relationships for normal-tissue response. International Journal of Radiation Oncology Biology Physics 8(11), 1981-1997.

See Also

getBED, getEQD2

Examples

getIsoEffD(D1=50, fd1=2.5, fd2=3, ab=c(2, 3, 4))