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DeconRNASeq (version 1.14.0)

decon.bootstrap: Estimate the confidence interval for the proportions predicted by deconvolution

Description

A function is used to estimate the the confidence interval for the proportions predicted by deconvolution through bootstrapping.

Usage

decon.bootstrap(data.set, possible.signatures, n.sig, n.iter)

Arguments

data.set
the data object for mixing samples
possible.signatures
a data frame providing the expression values from pure tissue samples
n.sig
the number of genes/transcripts used for estimation of proportions from our deconvolution
n.iter
the number of bootstraps for our deconvolution

Value

A three dimentional array to store means and 95% confidence interval

References

Gong, T., et al. (2011) Optimal Deconvolution of Transcriptional Profiling Data Using Quadratic Programming with Application to Complex Clinical Blood Samples, PLoS One, 6, e27156.