A computer program to detect markers responding to selection
Description
In the new era of population genomics, surveys of genetic
polymorphism ("genome scans") offer the opportunity to
distinguish locus-specific from genome wide effects at many
loci. Identifying presumably neutral regions of the genome that
are assumed to be influenced by genome-wide effects only, and
excluding presumably selected regions, is therefore critical to
infer population demography and phylogenetic history reliably.
Conversely, detecting locus-specific effects may help identify
those genes that have been, or still are, targeted by natural
selection. The software package DetSel has been developed to
identify markers that show deviation from neutral expectation
in pairwise comparisons of diverging populations.