[INTERNAL] Based on the supplied target molecules, interaction table, graph and annotation this function returns a data frame containing nodes in the network targeted by a drug and a list containing the drug names as names and a vector of node IDs as keys.
find_targets(graphs, target_molecules, interaction_table, annotation, on)A named list. Element `target_nodes` is a data frame with column `node_id` (unique node IDs in the iGraph graph object that are targeted by drugs) and columns `groupA` and `groupB` (bool values specifying whether the node is contained in the combined graph of the group). Element `drugs_to_target_nodes` contains a named list: elements are `drug_names` and contain a vector of node IDs that are their specific targets.
[list] List of two iGraph graph objects (one for each group)
[string] Identifies the type of the target molecules (e.g., `protein`). The string must be contained in the `type` column of the annotation data frame.
[data.frame] Specifying the interaction of drugs and target molecules. Must contain a column `drug_name` containing drug names/identifiers and a column named like the character string given in the `on` argument, which must be an identifier for the targeted molecule.
[data.frame] Contains the annotation for all the nodes contained in the combined network. Must contain a column `node_id` (vertex IDs in iGraph graph object) and a column named like the character string given in the `on` argument, which must be an identifier for the targeted molecule.
[string] Defines the ID that is used to match drugs to their targets. Both supplied data frames (`annotation` and `interaction_table`) must contain a column named like this character string.