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DrInsight (version 0.1.2)

Drug Repurposing: Integration and Systematic Investigation of Genomic High Throughput Data

Description

This is a connectivity mapping-based drug repurposing tool that identifies drugs that can potentially reverse query disease phenotype or have similar functions with query drugs.

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Version

Install

install.packages('DrInsight')

Monthly Downloads

12

Version

0.1.2

License

GPL-2

Maintainer

Jinyan Chan

Last Published

June 3rd, 2020

Functions in DrInsight (0.1.2)

network.graph

Plot Drug and Pathway Interaction Network
make.cytoscape.network

Drug and Pathway connection output files for Cytoscape visulization
example.drug.profiles

An example cmap drug reference profiles
example.pathway

example.pathway
brca.tcga

A sample breast cancer gene differential expression analysis t statistic score data
drug.ident

Dr. Insight Drug Identification
CEG.network.graph

Plot The Pathway-CEG Network for A Drug
drug.info

The matrix containing the drug instances information of CMap drug data
pathway.analysis

Drug Mechanism of Action Pathway Analysis
probe.to.genes

The matrix of Affymetrix probe IDs and gene symbols relationship
get.cmap.ref

Read In and Process CMap Reference Profiles
pathway.PID

pathway.PID
example.disease

An example gene differential expression analysis test statistic score data