DriverNet (version 1.12.0)

computeDrivers: Compute a list of driver mutations

Description

Use a greedy algorithm to rank a list of driver mutations.

Usage

computeDrivers(patMutMatrix, patOutMatrix, influenceGraph, outputFolder = NULL, 
printToConsole = FALSE, weighted = FALSE)

Arguments

patMutMatrix

Patient Mutation Matrix

patOutMatrix

Patient Outlier Matrix

influenceGraph

Influence Graph Matrix

outputFolder

The folder to store the log. If set to NULL, no log files will be written. If set to "", the log will be written to the current folder.

printToConsole

If set to TRUE, progress and result of the function will be printed to the console.

weighted

Must be set to FALSE in this version.

Value

An object of DriverNetResult class that can be passed to the resultSummary method.

Examples

data(samplePatientMutationMatrix)
data(samplePatientOutlierMatrix)
data(sampleInfluenceGraph)
driversList = computeDrivers(samplePatientMutationMatrix, samplePatientOutlierMatrix, 
sampleInfluenceGraph, outputFolder=NULL, printToConsole=FALSE)

drivers(driversList)[1:10]