plotDruglink

The function "plotDruglink" is used to plot a bipartite network of drugs and shared molecular functions.

A systematic biology tool was developed to repurpose drugs via a drug-drug functional similarity network. 'DrugSim2DR' first predict drug-drug functional similarity  in the context of specific disease, and then using the similarity constructed a weighted drug similarity network. Finally, it used a network propagation algorithm on the network to identify drugs with significant target abnormalities as candidate drugs.

Junwei Han

DrugSim2DR

Predict Drug Functional Similarity to Drug Repurposing

Ji Li

Jiashuo Wu

plotDruglink function

<dl><dt>drug1</dt>
<dd>The drugbank ID of drug1.</dd>
<dt>drug2</dt>
<dd>The drugbank ID of drug2.</dd>
<dt>i</dt>
<dd>Specifies the number of outputs molecular functions, which is 5 by default.</dd>
<dt>color_MF</dt>
<dd>Defines the color of MF nodes in the network.</dd>
<dt>color_drug</dt>
<dd>Defines the color of drug nodes in the network.</dd>
<dt>layout_type</dt>
<dd>layout_type used to set the appropriate arrangement, there is an option to choose from "circle","dh",and "sugiyama".</dd></dl>

Arguments

plotDruglink — plotDruglink

<dl>

<dt>drug1</dt>
<dd>The drugbank ID of drug1.</dd>


<dt>drug2</dt>
<dd>The drugbank ID of drug2.</dd>


<dt>i</dt>
<dd>Specifies the number of outputs molecular functions, which is 5 by default.</dd>


<dt>color_MF</dt>
<dd>Defines the color of MF nodes in the network.</dd>


<dt>color_drug</dt>
<dd>Defines the color of drug nodes in the network.</dd>


<dt>layout_type</dt>
<dd>layout_type used to set the appropriate arrangement, there is an option to choose from "circle","dh",and "sugiyama".</dd>

</dl>

plotDruglink: plotDruglink

Description

Usage

Value

Arguments

Examples