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EQUIVNONINF (version 1.0.2)

Testing for Equivalence and Noninferiority

Description

Making available in R the complete set of programs accompanying S. Wellek's (2010) monograph ''Testing Statistical Hypotheses of Equivalence and Noninferiority. Second Edition'' (Chapman&Hall/CRC).

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install.packages('EQUIVNONINF')

Monthly Downloads

215

Version

1.0.2

License

CC0

Maintainer

Stefan Wellek

Last Published

July 12th, 2021

Functions in EQUIVNONINF (1.0.2)

EQUIVNONINF-package

Testing for equivalence and noninferiority
EQUIVNONINF-internal

Internal Equiv_Noninf Functions
bi2aeq1

Power of the exact Fisher type test for equivalence
bi1st

Critical constants and power of the UMP test for equivalence of a single binomial proportion to some given reference value
bi2diffac

Determination of a corrected nominal significance level for the asymptotic test for equivalence of two unrelated binomial proportions with respect to the difference \(\delta\) of their population counterparts
bi2by_ni_OR

Objective Bayesian test for noninferiority in the two-sample setting with binary data and the odds ratio as the parameter of interest
bi2aeq2

Sample sizes for the exact Fisher type test for equivalence
bi2aeq3

Determination of a maximally raised nominal significance level for the nonrandomized version of the exact Fisher type test for equivalence
bi2dipow

Exact rejection probability of the asymptotic test for equivalence of two unrelated binomial proportions with respect to the difference of their expectations at any nominal level under an arbitrary parameter configuration
bi2by_ni_del

Objective Bayesian test for noninferiority in the two-sample setting with binary data and the difference of the two proportions as the parameter of interest
cf_reh_midp

Mid-p-value - based confidence bounds to the relative excess heterozygosity (REH) exhibited by a SNP genotype distribution
bi2rlv2

Sample sizes for the exact Fisher type test for relevant differences
bi2rlv1

Power of the exact Fisher type test for relevant differences
bi2ste2

Sample sizes for the exact Fisher type test for noninferiority
bi2ste3

Determination of a maximally raised nominal significance level for the nonrandomized version of the exact Fisher type test for noninferiority
mcnemasc

Determination of a corrected nominal significance level for the asymptotic test for equivalence of two paired binomial proportions with respect to the difference of their expectations (McNemar setting)
bi2ste1

Power of the exact Fisher type test for noninferiority
gofhwex_1s

Critical constants of the exact UMPU test for absence of a substantial deficit of heterozygotes as compared with a HWE-compliant SNP genotype distribution [noninferiority version of the test implemented by means of gofhwex]
bi2st

Critical constants for the exact Fisher type UMPU test for equivalence of two binomial distributions with respect to the odds ratio
gofind_t

Establishing approximate independence in a two-way contingency table: Test statistic and critical bound
mcnby_ni_pp

Computation of the posterior probability of the alternative hypothesis of noninferiority in the McNemar setting, given a specific point in the sample space
mawi

Mann-Whitney test for equivalence of two continuous distributions of arbitrary shape: test statistic and critical upper bound
exp1st

Critical constants and power against the null alternative of the UMP test for equivalence of the hazard rate of a single exponential distribution to some given reference value
gofsimpt

Establishing goodness of fit of an observed to a fully specified multinomial distribution: test statistic and critical bound
mcnasc_ni

Determination of a corrected nominal significance level for the asymptotic test for noninferiority in the McNemar setting
sgnrk

Signed rank test for equivalence of an arbitrary continuous distribution of the intraindividual differences in terms of the probability of a positive sign of a Walsh average: test statistic and critical upper bound
po_pbibe

Bayesian posterior probability of the alternative hypothesis of probability-based individual bioequivalence (PBIBE)
mwtie_xy

Distribution-free two-sample equivalence test for tied data: test statistic and critical upper bound
powsign

Nonconditional power of the UMPU sign test for equivalence and its nonrandomized counterpart
bi2wld_ni_del

Function to compute corrected nominal levels for the Wald type (asymptotic) test for one-sided equivalence of two binomial distributions with respect to the difference of success rates
fstretch

Critical constants and power of the UMPI (uniformly most powerful invariant) test for dispersion equivalence of two Gaussian distributions
mcnby_ni

Bayesian test for noninferiority in the McNemar setting with the difference of proportions as the parameter of interest
srktie_d

Generalized signed rank test for equivalence for tied data: test statistic and critical upper bound
cf_reh_exact

Exact confidence bounds to the relative excess heterozygosity (REH) exhibited by a SNP genotype distribution
gofhwex

Critical constants of the exact UMPU test for approximate compatibility of a SNP genotype distribution with the Hardy-Weinberg model
mcnempow

Exact rejection probability of the asymptotic test for equivalence of two paired binomial proportions with respect to the difference of their expectations (McNemar setting)
tt1st

Critical constants and power against the null alternative of the one-sample t-test for equivalence with an arbitrary, maybe nonsymmetric choice of the limits of the equivalence range
tt2st

Critical constants and power against the null alternative of the two-sample t-test for equivalence with an arbitrary, maybe nonsymmetric choice of the limits of the equivalence range
mwtie_fr

Analogue of mwtie_xy for settings with grouped data
pow_abe

Confidence innterval inclusion test for average bioequivalence: exact power against an arbitrary specific alternative
postmys

Bayesian posterior probability of the alternative hypothesis in the setting of the one-sample t-test for equivalence
srktie_m

Analogue of srktie_d for settings where the distribution of intraindividual differences is concentrated on a finite lattice