EWCE (version 1.0.2)

mouse_to_human_homologs: Table of Human-->Mouse orthologs for all human genes

Description

A dataset containing the MGI and HGNC symbols, Human and Mouse Entrez and Ensembl gene IDs for all human orthologs for mouse genes. Whenin the mouse genes are defined based on a list of all MGI markers from the MGI website (downloaded as MRK_List2.rpt file from http://goo.gl/mjf2GQ)

Usage

mouse_to_human_homologs

Format

An object of class data.frame with 21508 rows and 6 columns.

Examples

## Not run: 
# ## The code to prepare the .Rda file file from the marker file is:
# markers = read.csv("MRK_List2.rpt",sep="\t")
# genes = markers[markers$Feature.Type=="protein coding gene",]
# listMarts(host="www.ensembl.org")
# human <- useMart(host="www.ensembl.org", "ENSEMBL_MART_ENSEMBL", dataset="hsapiens_gene_ensembl")
# mouse <- useMart(host="www.ensembl.org", "ENSEMBL_MART_ENSEMBL", dataset="mmusculus_gene_ensembl")
# mouse_to_human_homologs = getLDS(attributes = c("mgi_symbol","entrezgene","ensembl_gene_id"),
#                                  filters = "mgi_symbol", values = genes$Marker.Symbol,
#                                  mart = mouse,
#                                  attributesL = c("hgnc_symbol","ensembl_gene_id","entrezgene"), martL = human)
# save(mouse_to_human_homologs,file="mouse_to_human_homologs.Rda")
# ## End(Not run)