EWOC2 (version 1.0)

mtdcurve: Generating MTD curve based on logistic model for two drugs

Description

Generating MTD curve based on logistic model for two drugs

Usage

mtdcurve(rho00, rho01, rho10, eta, theta)

Arguments

rho00

a numeric value indicating the true value of the parameter rho00, the probability of DLT when the levels of drugs A and B are both 0

rho01

a numeric value indicating the true value of the parameter rho01, the probability of DLT when the levels of drugs A and B are 0 and 1, respectively

rho10

a numeric value indicating the true value of the parameter rho10, the probability of DLT when the levels of drugs A and B are 1 and 0, respectively

eta

a numeric value indicating the true value of the eta, the interaction parameter

theta

a numerical value defining the proportion of expected patients to experience a medically unacceptable, dose-limiting toxicity (DLT) if administered the MTD

Value

none

Examples

# NOT RUN {
mtdcurve(rho00=0.01, rho01=0.2, rho10=0.9, eta=20, theta=0.2)
# }