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Epi (version 2.48)

Statistical Analysis in Epidemiology

Description

Functions for demographic and epidemiological analysis in the Lexis diagram, i.e. register and cohort follow-up data. In particular representation, manipulation, rate estimation and simulation for multistate data - the Lexis suite of functions, which includes interfaces to 'mstate', 'etm' and 'cmprsk' packages. Contains functions for Age-Period-Cohort and Lee-Carter modeling and a function for interval censored data and some useful functions for tabulation and plotting, as well as a number of epidemiological data sets.

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Version

Install

install.packages('Epi')

Monthly Downloads

8,952

Version

2.48

License

GPL-2

Maintainer

Bendix Carstensen

Last Published

March 31st, 2024

Functions in Epi (2.48)

Life.lines

Compute dates/ages for life lines in a Lexis diagram
Lexis.lines

Draw life lines in a Lexis diagram.
Lexis.diagram

Plot a Lexis diagram
addCov.Lexis

Add covariates (typically clinical measurements) taken at known times to a Lexis object.
bdendo

A case-control study of endometrial cancer
apc.frame

Produce an empty frame for display of parameter-estimates from Age-Period-Cohort-models.
NArray

Set up an array of NAs, solely from the list of dimnames
addDrug.Lexis

Expand a Lexis object with information of drug exposure based on purchase dates and -amounts
Y.dk

Population risk time in Denmark
Termplot

A wrapper for termplot that optionally (but by default) exponentiates terms, and plot them on a common log-scale. Also scales x-axes to the same physical scale.
N2Y

Create risk time ("Person-Years") in Lexis triangles from population count data.
brv

Bereavement in an elderly cohort
ci.lin

Compute linear functions of parameters with standard errors and confidence limits, optionally transforming to a different scale.
cal.yr

Functions to convert character, factor and various date objects into a number, and vice versa.
ci.cum

Compute cumulative sum of estimates.
Ns

Natural splines - (cubic splines linear beyond outermost knots) with convenient specification of knots and possibility of centering, detrending and clamping.
N.dk

Population size in Denmark
M.dk

Mortality in Denmark 1974 ff.
ccwc

Generate a nested case-control study
ci.Crisk

Compute cumulative risks and expected sojourn times from models for cause-specific rates.
crr.Lexis

Fit a competing risks regression model (Fine-Gray model) using a Lexis object)
bootLexis

Create a bootstrap sample of persons (as identified by lex.id) from a Lexis object
contr.cum

Contrast matrices
ROC

Function to compute and draw ROC-curves.
boxes.MS

Draw boxes and arrows for illustration of multistate models.
Relevel

Reorder and combine levels of a factor
diet

Diet and heart data
apc.LCa

Fit Age-Period-Cohort models and Lee-Carter models with effects modeled by natural splines.
cutLexis

Cut follow-up at a specified date for each person.
effx

Function to calculate effects
ci.pd

Compute confidence limits for a difference of two independent proportions.
clogistic

Conditional logistic regression
apc.fit

Fit an Age-Period-Cohort model to tabular data.
detrend

Projection of a model matrix on the orthogonal complement of a trend or curvature.
fit.add

Fit an additive excess risk model to interval censored data.
S.typh

Salmonella Typhimurium outbreak 1996 in Denmark.
fit.baseline

Fit a piecewise contsnt intesity model for interval censored data.
gen.exp

Generate covariates for drug-exposure follow-up from drug purchase records.
lep

An unmatched case-control study of leprosy incidence
lgrep

Convenience versions of grep
fit.mult

Fits a multiplicative relative risk model to interval censored data.
gmortDK

Population mortality rates for Denmark in 5-years age groups.
float

Calculate floated variances
births

Births in a London Hospital
blcaIT

Bladder cancer mortality in Italian males
effx.match

Function to calculate effects for individually matched case-control studies
erl

Compute survival functions from rates and expected residual lifetime in an illness-death model as well as years of life lost to disease.
nickel

A Cohort of Nickel Smelters in South Wales
plotCIF

Plotting Aalen-Johansen curves for competing events
occup

A small occupational cohort
plotEst

Plot estimates with confidence limits (forest plot)
rateplot

Functions to plot rates from a table classified by age and calendar time (period)
cbind.Lexis

Combining a Lexis objects with data frames or other Lexis objects
lungDK

Male lung cancer incidence in Denmark
thoro

Thorotrast Study
timeBand

Extract time band data from a split Lexis object
foreign.Lexis

Create a data structures suitable for use with packages mstate or etm.
ncut

Function to group a variable in intervals.
apc.lines

Plot APC-estimates in an APC-frame.
nice

Nice breakpoints
lls

Functions to manage and explore the workspace
ewrates

Rates of lung and nasal cancer mortality, and total mortality.
mat2pol

Plot columns of a matrix as stacked areas.
mod.Lexis

Fit intensity models to follow-up data in Lexis objects
mortDK

Population mortality rates for Denmark in 1-year age-classes.
ftrend

Fit a floating trend to a factor in generalized linear model
expand.data

Function to expand data for regression analysis of interval censored data.
in.span

Is x in the column span of matrix A and what columns are linearly dependent?
hivDK

hivDK: seroconversion in a cohort of Danish men
harm

Create a basis of harmonic functions.
plot.Lexis

Lexis diagrams
poisreg

Family Object for Poisson Regression
plotevent

Plot Equivalence Classes
stat.table

Tables of summary statistics
pc.lines

Plot period and cohort effects in an APC-frame.
stattable.funs

Special functions for use in stat.table
plot.apc

Plot the estimates from a fitted Age-Period-Cohort model
legendbox

Draw a box with text explaining the numbers in and between boxes from boxes.MS and boxes.Lexis
merge.Lexis

Merge a Lexis object with a data frame
mh

Mantel-Haenszel analyses of cohort and case-control studies
simLexis

Simulate a Lexis object representing follow-up in a multistate model.
summary.Lexis

Summarize transitions and risk time from a Lexis object
splitLexis

Split follow-up time in a Lexis object
pctab

Create percentages in a table
matshade

Plot confidence intervals as shaded areas around lines.
testisDK

Testis cancer incidence in Denmark, 1943--1996
steno2

Clinical trial: Steno2 baseline and follow-up.
mcutLexis

Cut follow-up at multiple event dates and keep track of order of events
pr

Diabetes prevance as of 2010-01-01 in Denmark
projection.ip

Projection of columns of a matrix.
subset.Lexis

Subsetting Lexis (and stacked.Lexis) objects
rcutLexis

A function to cut follow-up at intermediate event times.
rm.tr

Remove transitions from a Lexis object.
timeScales

The time scales of a Lexis object
stack.Lexis

Functions to facilitate analysis of multistate models.
entry.Lexis

Time series and other methods for Lexis objects
unLexis

Remove Lexis attributes from a Lexis object.
twoby2

Analysis of a two by two table
transform.Lexis

Transform a Lexis (or stacked.Lexis) object
BrCa

Clinical status, relapse, metastasis and death in 2982 women with breast cancer.
Epi

Epi: Functions for manipulation and statistical analysis of epidemiological data
AaJ.Lexis

The Aalen-Johansen estimator of state probabilities from a multistate Lexis object.
DMepi

Epidemiological rates for diabetes in Denmark 1996--2015
DMlate

The Danish National Diabetes Register.
LCa.fit

Fit Lee-Carter-type models for rates to arbitrarily shaped observations of rates in a Lexis diagram.
B.dk

Births in Denmark by year and month of birth and sex
Lexis

Create a Lexis object of follow-up
DMconv

Conversion to diabetes
Icens

Fits a regression model to interval censored data.
Lexis2msm

Convert a Lexis obejct to a data set suitable for input to the msm:msm function.