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Epi (version 2.60)

Statistical Analysis in Epidemiology

Description

Functions for demographic and epidemiological analysis in the Lexis diagram, i.e. register and cohort follow-up data. In particular representation, manipulation, rate estimation and simulation for multistate data - the Lexis suite of functions, which includes interfaces to 'mstate', 'etm' and 'cmprsk' packages. Contains functions for Age-Period-Cohort and Lee-Carter modeling and a function for interval censored data and some useful functions for tabulation and plotting, as well as a number of epidemiological data sets.

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Version

Install

install.packages('Epi')

Monthly Downloads

6,284

Version

2.60

License

GPL-2

Maintainer

Bendix Carstensen

Last Published

July 8th, 2025

Functions in Epi (2.60)

M.dk

Mortality in Denmark 1974 ff.
NArray

Set up an array of NAs, solely from the list of dimnames
Lexis2msm

Convert a Lexis obejct to a data set suitable for input to the msm:msm function.
N2Y

Create risk time ("Person-Years") in Lexis triangles from population count data.
N.dk

Population size in Denmark
Ns

Natural splines - (cubic splines linear beyond outermost knots) with convenient specification of knots and possibility of centering, detrending and clamping.
ROC

Function to compute and draw ROC-curves.
Life.lines

Compute dates/ages for life lines in a Lexis diagram
Lexis.diagram

Plot a Lexis diagram
Lexis.lines

Draw life lines in a Lexis diagram.
Termplot

A wrapper for termplot that optionally (but by default) exponentiates terms, and plot them on a common log-scale. Also scales x-axes to the same physical scale.
S.typh

Salmonella Typhimurium outbreak 1996 in Denmark.
Relevel

Reorder and combine levels of a factor
apc.frame

Produce an empty frame for display of parameter-estimates from Age-Period-Cohort-models.
apc.LCa

Fit Age-Period-Cohort models and Lee-Carter models with effects modeled by natural splines.
Y.dk

Population risk time in Denmark
apc.fit

Fit an Age-Period-Cohort model to tabular data.
bdendo

A case-control study of endometrial cancer
addCov

Add covariates (typically clinical measurements) taken at known times to a Lexis object.
addDrug

Expand a Lexis object with information of drug exposure based on purchase dates and -amounts
bootLexis

Create a bootstrap sample of persons (as identified by lex.id) from a Lexis object
blcaIT

Bladder cancer mortality in Italian males
births

Births in a London Hospital
boxes.MS

Draw boxes and arrows for illustration of multistate models.
brv

Bereavement in an elderly cohort
cal.yr

Functions to convert character, factor and various date objects into a number, and vice versa.
ci.Crisk

Compute cumulative risks and expected sojourn times from models for cause-specific rates.
ccwc

Generate a nested case-control study
ci.cum

Compute cumulative sum of estimates.
ci.eta

Linear predictor (eta) from a formula, coefficients, vcov and a prediction frame.
clogistic

Conditional logistic regression
cutLexis

Cut follow-up at a specified date for each person.
crr.Lexis

Fit a competing risks regression model (Fine-Gray model) using a Lexis object)
contr.cum

Contrast matrices
diet

Diet and heart data
detrend

Projection of a model matrix on the orthogonal complement of a trend or curvature.
float

Calculate floated variances
ftrend

Fit a floating trend to a factor in generalized linear model
ci.pd

Compute confidence limits for a difference of two independent proportions.
ci.lin

Compute linear functions of parameters with standard errors and confidence limits, optionally transforming to a different scale.
fit.add

Fit an additive excess risk model to interval censored data.
fit.baseline

Fit a piecewise contsnt intesity model for interval censored data.
fit.mult

Fits a multiplicative relative risk model to interval censored data.
expand.data

Function to expand data for regression analysis of interval censored data.
lgrep

Convenience versions of grep
apc.lines

Plot APC-estimates in an APC-frame.
foreign.Lexis

Create a data structures suitable for use with packages mstate or etm.
lungDK

Male lung cancer incidence in Denmark
lls

Functions to manage and explore the workspace
gen.exp

Generate covariates for drug-exposure follow-up from drug purchase records.
nice

Nice breakpoints for axes on plots
in.span

Is x in the column span of matrix A and what columns are linearly dependent?
mod.Lexis

Fit intensity models to follow-up data in Lexis objects
mat2pol

Plot columns of a matrix as stacked areas.
nickel

A Cohort of Nickel Smelters in South Wales
matshade

Plot confidence intervals as shaded areas around lines.
hivDK

hivDK: seroconversion in a cohort of Danish men
ncut

Function to group a variable in intervals.
mh

Mantel-Haenszel analyses of cohort and case-control studies
mortDK

Population mortality rates for Denmark in 1-year age-classes.
legendbox

Draw a box with text explaining the numbers in and between boxes from boxes.MS and boxes.Lexis
lep

An unmatched case-control study of leprosy incidence
paths.Lexis

Generate paths travelled through a Lexis multistate model data frame.
effx

Function to calculate effects
occup

A small occupational cohort
plotevent

Plot Equivalence Classes
plot.apc

Plot the estimates from a fitted Age-Period-Cohort model
plot.Lexis

Lexis diagrams
effx.match

Function to calculate effects for individually matched case-control studies
gmortDK

Population mortality rates for Denmark in 5-years age groups.
ewrates

Rates of lung and nasal cancer mortality, and total mortality.
mcutLexis

Cut follow-up at multiple event dates and keep track of order of events
erl

Compute survival functions from rates and expected residual lifetime in an illness-death model as well as years of life lost to disease.
plotCIF

Plotting Aalen-Johansen curves for competing events
harm

Create a basis of harmonic functions.
merge.Lexis

Merge a Lexis object with a data frame
rateplot

Functions to plot rates from a table classified by age and calendar time (period)
plotEst

Plot estimates with confidence limits (forest plot)
cbind.Lexis

Combining a Lexis objects with data frames or other Lexis objects
rcutLexis

A function to cut follow-up at intermediate event times.
poisreg

Family Object for Poisson Regression
stack.Lexis

Functions to facilitate analysis of multistate models.
entry.Lexis

Time series and other methods for Lexis objects
unLexis

Remove Lexis attributes from a Lexis object.
timeScales

The time scales of a Lexis object
summary.Lexis

Summarize transitions and risk time from a Lexis object
transform.Lexis

Transform a Lexis (or stacked.Lexis) object
testisDK

Testis cancer incidence in Denmark, 1943--1996
twoby2

Analysis of a two by two table
pc.lines

Plot period and cohort effects in an APC-frame.
stat.table

Tables of summary statistics
stattable.funs

Special functions for use in stat.table
simLexis

Simulate a Lexis object representing follow-up in a multistate model.
pctab

Create percentages in a table
rm.tr

Remove transitions from a Lexis object.
timeBand

Extract time band data from a split Lexis object
subset.Lexis

Subsetting Lexis (and stacked.Lexis) objects
pr

Diabetes prevance as of 2010-01-01 in Denmark
projection.ip

Projection of columns of a matrix.
splitLexis

Split follow-up time in a Lexis object
thoro

Thorotrast Study
steno2

Clinical trial: Steno2 baseline and follow-up.
AaJ

The Aalen-Johansen estimator of state probabilities from a multistate Lexis object.
DMconv

Conversion to diabetes
DMepi

Epidemiological rates for diabetes in Denmark 1996--2015
BrCa

Clinical status, relapse, metastasis and death in 2982 women with breast cancer.
B.dk

Births in Denmark by year and month of birth and sex
DMlate

The Danish National Diabetes Register.
LCa.fit

Fit Lee-Carter-type models for rates to arbitrarily shaped observations of rates in a Lexis diagram.
Lexis

Create a Lexis object of follow-up
Epi

Epi: Functions for manipulation and statistical analysis of epidemiological data
Icens

Fits a regression model to interval censored data.