Chen_2016_event_time_piecewise_exp_abovetime0

generate event time under the delay-treatment effect and cured population setting

Predicts enrollment and events assumed enrollment and treatment-specific time-to-event models, and calculates test statistics for time-to-event data with cured population based on the simulation.Methods for prediction event in the existence of cured population are as described in : Chen, Tai-Tsang(2016) <doi:10.1186/s12874-016-0117-3>.

Bo Wei

EventPredInCure

Event Prediction Including Cured Population

Kaifeng Lu

Brent McHenry

Chen_2016_event_time_piecewise_exp_abovetime0 function

<dl><dt>u</dt>
<dd>a scalar with between 0 and 1, which is the conditional survival probability at the event time.</dd>
<dt>p</dt>
<dd>the proportion of cured population in the control arm</dd>
<dt>time0</dt>
<dd>the observed ongoing survival time</dd>
<dt>piecewiseSurvivalTime</dt>
<dd>A vector that specifies the time
intervals for the piecewise exponential survival distribution.
Must start with 0, e.g., c(0, 60) breaks the time axis into 2
event intervals: [0, 60) and [60, Inf). By default, it is set to 0.</dd>
<dt>piecewisehazard</dt>
<dd>A vector that specifies the hazard rate in
intervals for the piecewise exponential survival distribution.</dd></dl>

Arguments

Function to generate event time with piecewise exponential distribution for ongoing subject in the existence of cured population — Chen_2016_event_time_piecewise_exp_abovetime0

<dl>

<dt>u</dt>
<dd>a scalar with between 0 and 1, which is the conditional survival probability at the event time.</dd>


<dt>p</dt>
<dd>the proportion of cured population in the control arm</dd>


<dt>time0</dt>
<dd>the observed ongoing survival time</dd>


<dt>piecewiseSurvivalTime</dt>
<dd>A vector that specifies the time
intervals for the piecewise exponential survival distribution.
Must start with 0, e.g., c(0, 60) breaks the time axis into 2
event intervals: [0, 60) and [60, Inf). By default, it is set to 0.</dd>


<dt>piecewisehazard</dt>
<dd>A vector that specifies the hazard rate in
intervals for the piecewise exponential survival distribution.</dd>

</dl>

Chen_2016_event_time_piecewise_exp_abovetime0: Function to generate event time with piecewise exponential distribution for ongoing subject in the existence of cured population

Description

Usage

Value

Arguments

References