EventPredInCure (version 1.0)

tte: Calculating log-rank test p-value, median time from each arm, hazard ratio between two arms, number of subjects and events in time-to-event outcomes.

Description

Calculate log-rank test p-value, median time from each arm, HR between arms, number of subjects and events

Usage

tte(os, osc, grp, type, test = "Futility")

Value

If type='all', return a list that includes the log-rank p-value, median time from each arm, hazard ratio between arms, and 95% confidence interval of hazard ratio, number of subjects and events; and events If type='logrank', return a list that includes the log-rank p-value, number of subjects and events; If type='hr', return a list that includes hazard ratio between arms, and 95% confidence interval of hazard ratio

Arguments

os

Time to event variable

osc

Time to event censoring variable

grp

Treatment assignment indicator with 1 denoting the treated group, and 0 denoting the placebo group.

type

either "all" or "logrank" or "hr"

test

a character denotes the test type, include "Superiority","Futility","Two-sided"

Details

The control arm

Examples

n <- 500
event <- runif(n,1, 5)
osc<-1*(event<=4)
os <- pmin(event,4)
trt<-c(rep(0,n/2),rep(1,n/2))
tte(os,osc,trt,type='all')