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FacPad (version 3.0)

Bayesian Sparse Factor Analysis model for the inference of pathways responsive to drug treatment

Description

This method tries to explain the gene-wise treatment response ratios in terms of the latent pathways. It uses bayesian sparse factor modeling to infer the loadings (weights) of each pathway on its associated probesets as well as the latent factor activity levels for each treatment.

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Version

Install

install.packages('FacPad')

Monthly Downloads

24

Version

3.0

License

GPL (>= 2)

Maintainer

Haisu Ma

Last Published

March 27th, 2014

Functions in FacPad (3.0)

gibbs2

A Collapsed Gibbs Sampling Algorithm for the Inference of Sparse Bayesian Factor Models_version2
matrixY

The treatment response matrix
gibbs_sampling

A Collapsed Gibbs Sampling Algorithm for the Inference of Sparse Bayesian Factor Models
FacPad-package

Sparse factor modeling for the inference of drug-responsive pathways
matrixL

Pathway structure matrix L