GEWIST (version 1.16.0)

GEWIST-package: Gene Environment Wide Interaction Search Threshold

Description

This 'GEWIST' package provides statistical tools to efficiently optimize SNP prioritization for gene-gene and gene-environment interactions.

Details

Package:

PathWei

Type:

Package

Version:

0.99.z

License:

GPL-2

LazyLoad:

yes

References

Deng W.Q, Pare G. (2011) A fast algorithm to optimize SNP prioritization for gene-gene and gene-environment interactions. Genetic Epidemiology. 35: 729-738. doi: 10.1002/gepi.20624

Pare G, Cook NR, Ridker PM, Chasman DI (2010) On the Use of Variance per Genotype as a Tool to Identify Quantitative Trait Interaction Effects: A Report from the Women's Genome Health Study. PLoS Genet 6(6): e1000981. doi:10.1371/journal.pgen.1000981

Levene H. (1960) Robust tests for equality of variances. In Contributions to Probability and Statistics: Essays in Honor of Harold Hotelling eds:I. Olkin, S.G. Ghurye, W. Hoeffding, W.G. Madow & H.B.Mann, pp.278-292. Stanford: Stanford University Press.