GNGTools (version 1.0.0)

get.ts.bin.int.dec: Get two-sample binary interim decision

Description

Get two-sample binary interim decision

Usage

get.ts.bin.int.dec(
  a.con = 1,
  b.con = 1,
  a.trt = 1,
  b.trt = 1,
  n.trt = 40,
  n.con = 40,
  n.int.c = c(10, 20, 30),
  n.int.t = c(10, 20, 30),
  Delta.lrv = 0.15,
  Delta.tv = 0.3,
  tau.tv = 0.1,
  tau.lrv = 0.8,
  tau.ng = 0.65,
  go.thresh = 0.8,
  ng.thresh = 0.8,
  runs = 500,
  include_nogo = TRUE
)

Value

a Data frame with the following columns * **IntermR_C** the number of control responses * **IntermR_T** the number of treatment responses * **Interm** the index of which interim analysis is being assessed. * **Go/No-Go/Consider** the proportion of simulations generating a final go/No-Go/Consider decision. * **Decision** The interim decision based off of the simulated results.

Arguments

a.con

alpha parameter for control

b.con

beta parameter for control

a.trt

alpha parameter for treatment

b.trt

beta parameter for treatment

n.trt

final sample size for treatment

n.con

final sample size for control

n.int.c

interim sample sizes for control

n.int.t

interim sample sizes for treatment

Delta.lrv

min TPP

Delta.tv

Base TPP

tau.tv

study-end threshold for Base TPP

tau.lrv

study-end threshold for Min TPP

tau.ng

study-end threshold for NG

go.thresh

threshold for predictive probabilities at interim

ng.thresh

threshold for predictive probabilities at interim

runs

the number of simulation runs

include_nogo

logical

Examples

my.ts.bin.int.dec <- get.ts.bin.int.dec()
my.ts.bin.int.dec