GNGTools (version 1.0.0)

return.tte.int.data.req: Title

Description

Title

Usage

return.tte.int.data.req(
  m.con.prior = 0.001,
  m.trt.prior = 0.001,
  HR.prior = 1,
  ARatio = 1,
  interim.HR = c(0.8, 0.7, 0.65, 0.68, 0.7),
  interim.m = c(100, 200, 300, 400, 750),
  final.m = 1000,
  HR.tv = 0.7,
  HR.lrv = 0.9,
  tau.tv = 0.1,
  tau.lrv = 0.8,
  tau.ng = 0.65,
  HR.ng = NULL,
  HR.go = NULL,
  go.thresh = 0.8,
  ng.thresh = 0.8,
  include_nogo = TRUE
)

Value

A data.frame is returned

Arguments

m.con.prior

prior number of control events

m.trt.prior

prior number of treatment events

HR.prior

prior estimate for HR

ARatio

randomization ratio

interim.HR

Interim HR

interim.m

Interim events

final.m

final events

HR.tv

TPP Target Value aka Base TPP

HR.lrv

TPP Lower Reference Value aka Max TPP (large HRs lead to No-Go)

tau.tv

threshold associated with Base TPP

tau.lrv

threshold associated with Min TPP

tau.ng

threshold associated with No-Go

HR.ng

HR needed for ng; leave null for standard rule

HR.go

HR needed for go; leave null for standard rule

go.thresh

go threshold for predictive probability

ng.thresh

no-go threshold for predictive probability

include_nogo

logical

Examples

# \donttest{
holdit <- return.tte.int.data.req()
head(holdit)
# }