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GOTHiC (version 1.8.1)

Binomial test for Hi-C data analysis

Description

This is a Hi-C analysis package using a cumulative binomial test to detect interactions between distal genomic loci that have significantly more reads than expected by chance in Hi-C experiments. It takes mapped paired NGS reads as input and gives back the list of significant interactions for a given bin size in the genome.

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Version

Version

1.8.1

License

GPL-3

Maintainer

Borbala Mifsud

Last Published

February 15th, 2017

Functions in GOTHiC (1.8.1)

GOTHiChicup

Genome Organisation Through HiC from HiCUP output
pairReads

Function pairs aligned paired NGS reads
GOTHiC

Genome Organisation Through HiC
mapReadsToRestrictionSites

Function to map aligned and paired reads to the restriction fragments
filtered

A GenomicRangesList object used as an example in the GOTHiC package