stage_1_selection

<code>stage_1_selection</code> is used to determine the subgroup selected at the end of the first stage of GSED.

Provides function to apply "Group sequential enrichment design incorporating subgroup selection" (GSED) method proposed by Magnusson and Turnbull (2013) <doi:10.1002/sim.5738>.

Marie-Karelle Riviere

GSED

Group Sequential Enrichment Design

stage_1_selection function

<dl>
 
 <dt>N_subsets</dt>
<dd>Integer representing the number of possible subgroups.</dd> <dt>Z_1j</dt>
<dd>Vector containing the Z-statistics (standard normal under H0) for each subgroup. Must be of length <code>N_subsets</code>.</dd> <dt>l</dt>
<dd>Vector containing the lower boundaries for stagewise decisions.</dd> <dt>ordering</dt>
<dd>Boolean indicating if the subgroups (theta) are ordered.</dd> <dt>increasing_theta</dt>
<dd>Boolean indicating if greater values of theta parameters represent better treatment effects. The default value is set at FALSE.</dd></dl>

Arguments

Marie-Karelle Riviere-Jourdan <a href="/link/eldamjh%40gmail.com?package=GSED&version=2.6" data-mini-rdoc="GSED::eldamjh@gmail.com">eldamjh@gmail.com</a>

Author

Stage 1-selection step of GSED — stage_1_selection

<dl>
 
 <dt>N_subsets</dt>
<dd>Integer representing the number of possible subgroups.</dd>

 <dt>Z_1j</dt>
<dd>Vector containing the Z-statistics (standard normal under H0) for each subgroup. Must be of length <code>N_subsets</code>.</dd>

 <dt>l</dt>
<dd>Vector containing the lower boundaries for stagewise decisions.</dd>

 <dt>ordering</dt>
<dd>Boolean indicating if the subgroups (theta) are ordered.</dd>

 <dt>increasing_theta</dt>
<dd>Boolean indicating if greater values of theta parameters represent better treatment effects. The default value is set at FALSE.</dd>

</dl>

Marie-Karelle Riviere-Jourdan <a href='mailto:eldamjh@gmail.com'>eldamjh@gmail.com</a>

stage_1_selection: Stage 1-selection step of GSED

Description

Usage

Value

Arguments

Author

References

Examples