Description
Objects of the class Gsri contain the results of the GSRI analysis.
Objects from the class
Objects of class Gsri are returned by the gsri methods.Slots
result:- Data frame containing the results of the GSRI
estimation, with one row for each gene set and the columns:
pRegGenes:- Fraction of regulated genes in the gene set
pRegGenesSd:- Standard deviation of
pRegGenes obtained
from bootstrapping. nRegGenes:- Total number of regulated genes in the gene
set.
GSRI('alpha'%):- Gene Set Regulation Index, corresponding to
the alpha% quantile of the bootstrapped distribution.
nGenes:- Total number of genes in the gene set.
cdf:- List of data frames containing the ECDF of the
p-values. Each data frame covers one gene set, with the columns:
pval:- P-values obtained from the
test function. cdf:- Empirical cumulative density.
parms:- List containing the parameter values used in
the analysis, with the elements:
weight:- Weights for each gene in the gene set
nBoot:- Number of bootstraps for the calculation of the GSRI
test:- Statistical test function
alpha:- Confidence level for the GSRI
grenander:- Application of the Grenander estimatior in the
calculation of the ECDF
testArgs:- Optional arguments for
test function
Methods
Analysis:
- gsri:
-
signature(exprs="matrix", groups="factor",
geneSet="missing") signature(exprs="ExpressionSet", groups="factor",
geneSet="missing") signature(exprs="matrix", groups="factor",
geneSet="GeneSet") signature(exprs="ExpressionSet", groups="factor",
geneSet="GeneSet") signature(exprs="matrix", groups="factor",
geneSet="GeneSetCollection") signature(exprs="ExpressionSet", groups="factor",
geneSet="GeneSetCollection") Assess the degree of differential effect in the expression data.
Visualization:
- plot:
-
signature(x="Gsri", y=ANY)
Plot the empirical density of p-values and the corresponding estimated effect. Export to file:
- export:
-
signature(object="Gsri", file="character")
Get methods:
- getGsri:
-
signature(object="Gsri")
- getCdf:
-
signature(object="Gsri")
- getParms:
-
signature(object="Gsri")
Show:
- show:
-
signature(obejct="Gsri")
- summary:
-
signature(obejct="Gsri")