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GWAF (version 2.0)

GWAF-package: Genome-wide association/interaction analyses with family data

Description

For continuous traits, GWAF package provides two sets of functions for each of genome-wide association analyses and genome-wide interaction analyses with observed/imputed SNP genotypes for family data. One fits Linear Mixed Effects (LME) model and the other fits Generalized Estimation Equation (GEE) model to accounting for within pedigree correlation. While for dichotomous trait, GWAF package provides functions to fit GEE model for genome-wide association analyses and genome-wide interaction analyses. For LME, previous version of GWAF depends on kinship package that has been archived. In the current version, GWAF includes functions from kinship. In addition, GWAF package also provides functions for making genome-wide p-values plot and QQ plot that contains genomic control parameter estimate and generating scripts for genome-wide association analysis.

Arguments

docType

package

Details

ll{ Package: GWAF Type: Package Version: 2.0 Date: 2012-02-27 License: GPL (>= 2) }