GWAF-package: Genome-wide association/interaction analyses with family data
Description
For continuous traits, GWAF
package provides two sets of functions for each of genome-wide association analyses and genome-wide interaction analyses
with observed/imputed SNP genotypes for family data. One fits Linear Mixed Effects (LME) model and the other fits Generalized Estimation Equation (GEE) model
to accounting for within pedigree correlation. While for dichotomous trait, GWAF
package provides functions to fit GEE model for
genome-wide association analyses and genome-wide interaction analyses. For LME, previous version of GWAF
depends on kinship
package that has been archived.
In the current version, GWAF
includes functions from kinship
. In addition, GWAF
package
also provides functions for making genome-wide p-values plot and QQ plot that contains genomic control
parameter estimate and generating scripts for genome-wide association analysis.Details
ll{
Package: GWAF
Type: Package
Version: 2.0
Date: 2012-02-27
License: GPL (>= 2)
}