Usage
GeneticPower.Quantitative.Numeric( N=1000, delta=1, freq=0.15, minh=c("additive", "dominant", "recessive"), sigma=1, OtherParms=0, alpha=0.05, numtests=1, moi=NULL, rsquared=NULL)
GeneticPower.Quantitative.Factor( N=1000, delta=1, freq=0.15, minh=c("additive","dominant","recessive"), sigma=1, OtherParms=0, alpha=0.05, numtests=1, moi=NULL, rsquared=NULL)
Arguments
N
total samples in the analysis
delta
Treatment effect for an individual homozygote for the
disease allele ('b') relative to an individual homozygote for the
reference allele ('A')
freq
allele frequency of disease allele 'b'
minh
mode of inheritance: "additive","dominant","recessive",
Default is "additive". This parameter is OVER-RIDDEN by moi
.
sigma
standard deviation of the response phenotype
OtherParms
number of additional parameters (really, DOF) in the
model that will reduce your overall DOF
alpha
desired significance level
numtests
number of tests to be corrected by Bonferroni adjustment beforee achieving 'alpha'
moi
continuous value between 0 and 1 (inclusive) specifying the
mode of inheritance: 0 for recessive, 0.5 for additive, 1.0
for dominant. This parameter OVER-RIDES minh
.
rsquared
fraction of total sum-of-squares explained by
fit. This parameter OVER-RIDES delta
AND
sigma
.