# simulated data to use
set.seed(10)
ds <- data.frame(
ftime = rexp(200),
fstatus = sample(0:1,200,replace=TRUE),
x1 = runif(200),
x2 = runif(200),
x3 = runif(200))
library(survival)
library(rms)
dd <- datadist(ds)
options(datadist="dd")
s <- Surv(ds$ftime, ds$fstatus == 1)
fit <- cph(s ~ x1 + x2 + x3, data=ds)
if (isFitCoxPH(fit))
print("Correct, the cph is of cox PH hazard type")
fit <- coxph(s ~ x1 + x2 + x3, data=ds)
if (isFitCoxPH(fit))
print("Correct, the coxph is of cox PH hazard type")
library(cmprsk)
set.seed(10)
ftime <- rexp(200)
fstatus <- sample(0:2,200,replace=TRUE)
cov <- matrix(runif(600),nrow=200)
dimnames(cov)[[2]] <- c('x1','x2','x3')
fit <- crr(ftime,fstatus,cov)
if (isFitCoxPH(fit))
print(paste("Correct, the competing risk regression is",
"considered a type of cox regression",
"since it has a Hazard Ratio"))
# ** Borrowed code from the lrm example **
#Fit a logistic model containing predictors age, blood.pressure, sex
#and cholesterol, with age fitted with a smooth 5-knot restricted cubic
#spline function and a different shape of the age relationship for males
#and females.
n <- 1000 # define sample size
set.seed(17) # so can reproduce the results
age <- rnorm(n, 50, 10)
blood.pressure <- rnorm(n, 120, 15)
cholesterol <- rnorm(n, 200, 25)
sex <- factor(sample(c('female','male'), n,TRUE))
label(age) <- 'Age' # label is in Hmisc
label(cholesterol) <- 'Total Cholesterol'
label(blood.pressure) <- 'Systolic Blood Pressure'
label(sex) <- 'Sex'
units(cholesterol) <- 'mg/dl' # uses units.default in Hmisc
units(blood.pressure) <- 'mmHg'
#To use prop. odds model, avoid using a huge number of intercepts by
#grouping cholesterol into 40-tiles
# Specify population model for log odds that Y=1
L <- .4*(sex=='male') + .045*(age-50) +
(log(cholesterol - 10)-5.2)*(-2*(sex=='female') + 2*(sex=='male'))
# Simulate binary y to have Prob(y=1) = 1/[1+exp(-L)]
y <- ifelse(runif(n) < plogis(L), 1, 0)
cholesterol[1:3] <- NA # 3 missings, at random
ddist <- datadist(age, blood.pressure, cholesterol, sex)
options(datadist='ddist')
fit_lrm <- lrm(y ~ blood.pressure + sex * (age + rcs(cholesterol,4)),
x=TRUE, y=TRUE)
if (isFitLogit(fit_lrm) == TRUE)
print("Correct, the lrm is a logistic regression")
fit_lm <- lm(blood.pressure ~ sex)
if (isFitLogit(fit_lm) == FALSE)
print("Correct, the lm is not a logistic regression")
fit_glm_logit <- glm(y ~ blood.pressure + sex * (age + rcs(cholesterol,4)),
family = binomial())
if (isFitLogit(fit_glm_logit) == TRUE)
print("Correct, the glm with a family of binomial is a logistic regression")
fit_glm <- glm(blood.pressure ~ sex)
if (isFitLogit(fit_glm) == FALSE)
print("Correct, the glm without logit as a family is not a logistic regression")
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