HSAUR2 (version 1.1-17)

toenail: Toenail Infection Data

Description

Results of a clinical trial to compare two competing oral antifungal treatments for toenail infection.

Usage

data("toenail")

Arguments

Format

A data frame with 1908 observations on the following 5 variables.

patientID

a unique identifier for each patient in the trial.

outcome

degree of separation of the nail plate from the nail bed (onycholysis).

treatment

a factor with levels itraconazole and terbinafine.

time

the time in month when the visit actually took place.

visit

number of visit attended.

Details

De Backer et al. (1998) describe a clinical trial to compare two competing oral antifungal treatments for toenail infection (dermatophyte onychomycosis). A total of 378 patients were randomly allocated into two treatment groups, one group receiving 250mg per day of terbinafine and the other group 200mg per day of itraconazole. Patients were evaluated at seven visits, intended to be at weeks 0, 4, 8, 12, 24, 36, and 48 for the degree of separation of the nail plate from the nail bed (onycholysis) dichotomized into moderate or severe and none or mild. But patients did not always arrive exactly at the scheduled time and the exact time in months that they did attend was recorded. The data is not balanced since not all patients attended for all seven planned visits.

Examples

Run this code
# NOT RUN {
  data("toenail", package = "HSAUR2")


# }

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