In.house

This dataset gives the observed cross-tabulation of the test under evaluation (nucleic acid amplification test)  and the reference test.  In studies 1 and 2, the reference test was a culture test, in studies 3 and 4 it was a composite reference test of culture and clinical data (including signs, symptoms and clinical response to empiric TB therapy) and in studies 5 to 11 it was a composite reference test of culture and biopsy.

datasets

This package implements a model for joint meta-analysis of sensitivity and specificity of the diagnostic test under evaluation, while taking into account the possibly imperfect sensitivity and specificity of the reference test. This hierarchical model accounts for both within and between study variability. Estimation is carried out using a Bayesian approach, implemented via a Gibbs sampler. The model can be applied in situations where more than one reference test is used in the selected studies.

In.house: IN-HOUSE NUCLEIC ACID AMPLIFICATION TESTS (INH) FOR TB PLEURITIS

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