This dataset gives the observed cross-tabulation of the test under evaluation (nucleic acid amplification test) and the reference test. In studies 1 and 2, the reference test was a culture test, in studies 3 and 4 it was a composite reference test of culture and clinical data (including signs, symptoms and clinical response to empiric TB therapy) and in studies 5 to 11 it was a composite reference test of culture and biopsy.