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Harshlight (version 1.44.0)

A "corrective make-up" program for microarray chips

Description

The package is used to detect extended, diffuse and compact blemishes on microarray chips. Harshlight automatically marks the areas in a collection of chips (affybatch objects) and a corrected AffyBatch object is returned, in which the defected areas are substituted with NAs or the median of the values of the same probe in the other chips in the collection. The new version handle the substitute value as whole matrix to solve the memory problem.

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Version

Version

1.44.0

License

GPL (>= 2)

Maintainer

Maurizio Pellegrino

Last Published

February 15th, 2017

Functions in Harshlight (1.44.0)

HarshComp

a blemish detection program for microarray chips: extended and compact defects only
HarshExt

a blemish detection program for microarray chips: extended defects only
Harshlight

a blemish detection program for microarray chips: extended, diffuse, and compact defects
sim

blemish simulations from 100.000 random chips