createHiCDataset

An HTClist object from HiTC R package.

HTCL

A numeric vector of two values containing the distance interval used for Hi-C data analysis.

distInter

If verbose is True, then the different processing steps will be displayed.

verbose

This is an internal function (should not be used).

Here we propose a model to systematically analyze the roles of architectural proteins and functional elements in blocking long-range contacts between loci. The proposed model does not rely on topologically associating domain (TAD) mapping from Hi-C data. Instead of testing the enrichment or influence of protein binding at TAD borders, the model directly estimates the blocking effect of proteins on long-range contacts between flanking loci, making the model intuitive and biologically meaningful.

createHiCDataset: Create a dataset for further processing with the R package.

Description

Usage

Arguments

Value