GetExomeKmerCounts

A <code>ref.genome</code> argument as described in
<code><a rd-options="" href="/link/ICAMS?package=ICAMS&version=2.0.7" data-mini-rdoc="ICAMS::ICAMS">ICAMS</a></code>.

ref.genome

If given, homopolymers will be masked from
genome(sequence). Only simple repeat masking is accepted now.

filter.path

If <code>TRUE</code> generate progress messages.

verbose

A keyed data table which has exome ranges information.
It has three columns: chrom, start and end.

exome.range

Generate exome k-mer abundance from a given reference genome

internal

Analysis and visualization of experimentally elucidated mutational
signatures -- the kind of analysis and visualization in Boot et al.,
"In-depth characterization of the cisplatin mutational signature in
human cell lines and in esophageal and liver tumors", Genome Research 2018,
<doi:10.1101/gr.230219.117>. 'ICAMS' stands for In-depth Characterization
and Analysis of Mutational Signatures. 'ICAMS' has functions to read in
variant call files (VCFs) and to collate the corresponding catalogs of
mutational spectra and to analyze and plot catalogs of mutational spectra
and signatures. Handles both "counts-based" and "density-based" catalogs
of mutational spectra or signatures.

Steve Rozen

ICAMS

In-depth Characterization and Analysis of Mutational Signatures
('ICAMS')

GetExomeKmerCounts function

A <code>ref.genome</code> argument as described in
<code><a rd-options='' href='ICAMS'>ICAMS</a></code>.

GetExomeKmerCounts: Generate exome k-mer abundance from a given reference genome

Description

Usage

Arguments

Value