Create the matrix an SBS catalog for *one* sample from an in-memory VCF.
CreateOneColSBSMatrix(vcf, sample.id = "count", return.annotated.vcf = FALSE)
A list of three 1-column matrices with the names
catSBS96
, catSBS192
, catSBS1536
. If transcript
information is not available in vcf
, catSBS192
is not
generated. Do not rely on the order of elements in the list. If
return.annotated.vcf
= TRUE, another element annotated.vcf
will appear in the list. If there are SBS variants whose pentanucleotide
context contains "N", they will be excluded in the analysis and an
additional element discarded.variants
will appear in the return
list.
An in-memory VCF file annotated with sequence context and
transcript information by function AnnotateSBSVCF
. It must
*not* contain indels and must *not* contain DBS (double base
substitutions), or triplet base substitutions etc., even if encoded as
neighboring SBS.
Usually the sample id, but defaults to "count".
Whether to return the annotated VCF with additional columns showing the mutation class for each variant. Default is FALSE.