combinep_two

`combinep_two` combine two kinds of p-values,then,calculate z-score for them.

Identify Cancer Dysfunctional Sub-pathway by integrating gene expression, DNA methylation and copy number variation, and pathway topological information. 1)We firstly calculate the gene risk scores by integrating three kinds of data: DNA methylation, copy number variation, and gene expression.  2)Secondly, we perform a greedy search algorithm to identify the key dysfunctional sub-pathways within the pathways for which the discriminative scores were locally maximal. 3)Finally, the permutation test was used to calculate statistical significance level for these key dysfunctional sub-pathways.

Junwei Han

ICDS

Identification of Cancer Dysfunctional Subpathway with Omics
Data

Baotong Zheng

Siyao Liu

combinep_two function

<dl><dt>p1</dt>
<dd>A numeric vector of p-values or corrected p-values</dd>
<dt>p2</dt>
<dd>A numeric vector of p-values or corrected p-values</dd></dl>

Arguments

combinep_two — combinep_two

<dl>

<dt>p1</dt>
<dd>A numeric vector of p-values or corrected p-values</dd>


<dt>p2</dt>
<dd>A numeric vector of p-values or corrected p-values</dd>

</dl>

combinep_two: combinep_two

Description

Usage

Value

Arguments

Examples