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ISOpureR (version 1.1.3)

ISOpureS1.model_optimize.omega.omega_compute_loglikelihood: Compute loglikelihood relevant to omega for step 1

Description

Computes the part of the loglikelihood function relevant to optimizing omega for step 1

Usage

ISOpureS1.model_optimize.omega.omega_compute_loglikelihood(omega, tumordata, model)

Arguments

omega

(K-1)x1 matrix representing the weights of the normal profiles B_i used to make the weighted combination that forms the mean parameter vector for the Dirichlet distribution over m

tumordata

a GxD matrix representing gene expression profiles of tumor samples

model

list containing all the parameters to be optimized

Value

The part of the loglikelihood function relevant to optimizing omega