InteRD Integrated and robust cell-type deconvolution

InteRD has three primary advantages. First, it is able to effectively integrate deconvolution results from multiple scRNA-seq datasets. Second, InteRD calibrates estimates from reference-based deconvolution by taking into account extra biological information as priors. Third, InteRD is equipped with a data-driven mechanism of self-control designed to be robust to the introduction of inaccurate information in the deconvolution system.

Installation

You can install the released version of InteRD with:

#install devtools if necessary
install.packages("devtools")

#install the InteRD package
devtools::install_github("chencxxy28/InteRD")

#load
library(InteRD)

If Biobase package is not available, please install it first before installation of InteRD

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")
BiocManager::install("Biobase")

Vignettes

Please visit Tutorial.