Data from the Mayo Clinic trial in primary biliary cirrhosis (PBC) of the
liver. This dataset was obtained from the survival package:
the variables copper
and trig
from survival::pbc
were
merged into survival::pbcseq
and several categorical variables were
re-coded.
PBC
: A data frame of 312 individuals in long format with 1945 rows
and 21 variables.
case number
number of days between registration and the earlier of death, transplantation, or end of follow-up
status at endpoint ("censored", "transplant" or "dead")
D-pen (D-penicillamine) vs placebo
in years
male or female
urine copper (\(\mu\)g/day)
triglycerides (mg/dl)
number of days between enrolment and this visit date; all measurements below refer to this date
serum albumin (mg/dl)
alkaline phosphatase (U/liter)
presence of ascites
aspartate aminotransferase (U/ml)
serum bilirubin (mg/dl)
serum cholesterol (mg/dl)
"no": no oedema, "(un)treated": untreated or successfully treated 1 oedema, "edema": oedema despite diuretic therapy
presence of hepatomegaly (enlarged liver)
platelet count
standardised blood clotting time
blood vessel malformations in the skin
histologic stage of disease (4 levels)