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LDcorSV (version 1.3.4)

LDcorSV-package: LDcorSV

Description

The package provides a set of functions which aim is to propose four measures of linkage disequilibrium: - Measure.R2: the usual \(r^2\) measure.

- Measure.R2S: \(r^2\) corrected by the structure of the sample (\(r^2_S\)).

- Measure.R2V: \(r^2\) corrected by the relatedness of genotyped individuals (\(r^2_V\)).

- Measure.R2VS: \(r^2\) corrected by both the relatedness of genotyped individuals and the structure of the sample (\(r^2_VS\)).

- LD.Measures: this function computes the four measures of linkage disequilibrium (\(r^2\), \(r^2_V\), \(r^2_S\) and \(r^2_{VS}\)) for a set of loci and gives extra information about them.

Arguments

Author

David Desrousseaux, Florian Sandron, Aurélie Siberchicot, Christine Cierco-Ayrolles and Brigitte Mangin

Maintainer: aurelie.siberchicot@univ-lyon1.fr

References

Mangin, B., Siberchicot, A., Nicolas, S., Doligez, A., This, P., Cierco-Ayrolles, C. (2012). Novel measures of linkage disequilibrium that correct the bias due to population structure and relatedness. Heredity, 108 (3), 285-291. DOI: 10.1038/hdy.2011.73