# LDtests v1.0

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## Exact tests for Linkage Disequilibrium and Hardy-Weinberg Equilibrium

Exact tests for Linkage Disequilibrium (LD) and Hardy-Weinberg Equilibrium (HWE). - 2-sided LD tests based on different measures of LD (Kulinskaya and Lewin 2008) - 1-sided Fisher's exact test for LD - 2-sided Haldane test for HWE (Wiggington 2005) - 1-sided test for inbreeding - conditional p-values proposed in Kulinskaya (2008) to overcome the problems of asymetric distributions (for both LD and HWE)

## Functions in LDtests

 Name Description LD2sided.pvals P-values and Linkage Disequilibrium measures for several tests of Linkage Disequilibrium Fisher1sided 1-sided Fisher's test of linkage disequilibrium HWE2sided.table Table and plot of Hardy-Weinberg p-values for all 2x2 tables possible under the null distribution. LDtests-package Exact tests for Linkage Disequilibrium and Hardy-Weinberg Equilibrium HWE2sided P-values for three different tests of HWE LD2sided.tables Tables of p-values and Linkage Disequilibrium measures for all 2x2 tables possible under the null distribution. No Results!